Synthesis and radioiodination of 3-(E)-(2-iodovinyl)-N-acetyl-4- cysteaminylphenol, a putative tyrosinase substrate for imaging neutral crest tumours

DOI: 10.1002/(SICI)1099-1344(199805)41:5<355::AID-JLCR88>3.0.CO;2-K

Source and publish data:

Journal of labelled compounds and radiopharmaceuticals p. 355 - 361 (1998)

Update date:2022-08-03

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Authors:

Singh, Shradha

Jimbow, Kowichi

Kumar, Piyush

McEwan, Alexander J.

Wiebe, Leonard I.

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Article abstract of DOI:10.1002/(SICI)1099-1344(199805)41:5<355::AID-JLCR88>3.0.CO;2-K

The synthesis of 3-(E)-(2-iodovinyl)-N-acetyl-4-cysteaminylphenol (3- IV-N-Ac-4-SCAP) started from 3-iodophenol, which on condensation with cysteamine hydrochloride gave 3-iodo-4-cysteaminylphenol (1). Acetylation of 1 followed by selective deacetylation

Full text of DOI:10.1002/(SICI)1099-1344(199805)41:5<355::AID-JLCR88>3.0.CO;2-K

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