Desymmetrization of meso-1,2-diols via chiral oxazaborolidine-mediated ring-cleavage of acetal derivatives with silyl ketene S,O-acetal

Article abstract of DOI:10.1016/S0040-4039(98)00823-5

Desymmetrization of meso-1,2-diols leading to enantiomerically enriched MOM and MEM ethers is realized via chiral oxazaborolidine-mediated enantioselective ring-cleavage reaction of the acetal derivatives with silyl ketene S,O-acetal.