Dimers of 5HT1 ligands preferentially bind to 5HT(1B/1D) receptor subtypes

DOI: 10.1016/S0960-894X(98)00222-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1407 - 1412 (1998)

Update date:2022-08-04

Topics:

Authors:

Perez, Michel

Jorand-Lebrun, Catherine

Pauwels, Petrus J.

Pallard, Isabelle

Halazy, Serge

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00222-4

New dimers of known 5HT₁ ligands (SHT, 1-NP or 8-OH-DPAT) have been prepared and evaluated at human cloned 5HT(1B), 5HT(1D) and 5HT(1A) receptors. Binding experiments show that all these dimers have better affinities at 5HT(1B/1D) receptors tha

Full text of DOI:10.1016/S0960-894X(98)00222-4

Products guided by the article

Product name:[2-(5-{[4-(2-Chloro-acetylamino)-phenylcarbamoyl]-methoxy}-1H-indol-3-yl)-ethyl]-carbamic acid tert-butyl ester

Cas No:210545-94-1

R&D Labs maybe for 210545-94-1

Clearsynth Labs Limited

Contact:+91 - 22 - 26355700

Address:17, Lotus Business Park, Andheri West
Suzhou HeChuang Chemical Co.,Ltd.

Contact:+86-512-88800520

Address:No.9 Guanchao Rd,Changshu Advanced Materials Industy Park
Shanghai Coupling Pharmaceutical R&D Co., Ltd.(expird)

Contact:+86 021 50106671

Address:403 Room No.4 Buiding, No. 526 Ruiqing Road, Shanghai Zhangjiang Hi-Tech Park
Qingdao Kylin Trading Co., Ltd.

Contact:0086-532-68979884/58972912/68972263/65/88171519

Address:Room 2308,A building International Trade Center No.230 Changjiang Middle Road of Qingdao Economic Development Zone,Shandong,China.
Qingzhou Baibang import and export co.,Ltd

Contact:+86-536-3265899

Address:No.338, Tuoshan Road

Relevant to this article

Colorimetric macrocyclic anion probes bearing nitrophenylurea and nitrophenylthiourea binding groups

Doi:10.1016/j.tet.2013.04.016
(2013)
THE ANALOGS OF 8-D-HOMOARGININ-VASOPRESSIN WITH o-SUBSTITUTED PHENYLALANINE IN POSITION 2: SYNTHESIS AND SOME BIOLOGICAL PROPERTIES

Doi:10.1135/cccc19921103
(1992)
Fragmentation Selectivity in Electron Impact Ionization Mass Spectra of Substituted Dimethoxybenzenes

Doi:10.1002/oms.1210270613
(1992)
Induction of motion in a synthetic molecular machine: Effect of tuning the driving force

Doi:10.1002/chem.201204016
(2013)
Photochemistry of Nucleoside Transport Inhibitor 6-S-Benzylated Thiopurine Ribonucleosides. Implications for a New Class of Photoaffinity Labels

Doi:10.1021/jo00048a034
(1992)
Coordinative Cocatalysis via In³⁺. A Chemoselectivity Switch for Pd-Catalyzed Cycloadditions

Doi:10.1021/ja00046a041
(1992)

Article Doi