Tetrahedron p. 6841 - 6856 (1998)
Update date:2022-08-04
Topics:
Lang'at, Caroline C.
Watt, Robert A.
Toth, Istvan
Phillipson, J. David
The natural product quassin has been modified in order to produce compounds with potential antimalarial action. The modifications include demethylation, reduction of the keto function, esterification with simple organic acids and - to enhance the uptake through the biological barriers and increase the stability of the compounds - with lipoamino acids.
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