Synthesis and antiviral activity of L-2'-deoxy-2'-up-fluoro-4'- thionucleosides

Article abstract of DOI:10.1080/15257779908041497

L-2'-Deoxy-2'-up-fluoro-4'-thionucleosides were efficiently synthesized from D-xylose via L-4-thioarabitol derivative as a key intermediate and evaluated for antiviral activities against HIV-1, HSV-1,2 and HBV.

Full text of DOI:10.1080/15257779908041497

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Nucleosides and Nucleotides
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Synthesis and Antiviral Activity of L-2′-
Deoxy-2′-up-fluoro-4′-thionucleosides
Lak Shin Jeong a , Hyung Ryong Moon a , Su Jeong Yoo a , Sun Nan
Lee a , Hee-Doo Kim b & Moon Woo Chun c
a College of Pharmacy, Ewha Womans University , Seoul, 120-750,
Korea
b College of Pharmacy, Sookmyung Women's University , Seoul,
140-742, Korea
c College of Pharmacy, Seoul National University , Seoul, 151-742,
Korea
Published online: 04 Oct 2006.
To cite this article: Lak Shin Jeong , Hyung Ryong Moon , Su Jeong Yoo , Sun Nan Lee , Hee-Doo Kim &
Moon Woo Chun (1999) Synthesis and Antiviral Activity of L-2′-Deoxy-2′-up-fluoro-4′-thionucleosides,
Nucleosides and Nucleotides, 18:4-5, 571-572, DOI: 10.1080/15257779908041497
To link to this article: http://dx.doi.org/10.1080/15257779908041497
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