Bioorganic and Medicinal Chemistry Letters p. 1655 - 1660 (1998)
Update date:2022-08-03
Topics:
Hamilton, Robert
Walker, Brian
Walker, Brian J.
The synthesis of diphenyl phosphonate analogues of aspartic and glutamic acid, and their inhibitory activity against S. aureus V8 protease and granzyme B, is described. The study has revealed difficulties with protecting group compatibility in the synthesis of these analogues. Two analogues, Acetyl.Asp(P)(OPh)2 and Acetyl.Glu(P)(OPh)2 were found to function as irreversible inactivators of V8 proteinase, yet exhibit no activity against granzyme B.
View MoreDongguan Albiya Energy Science and Technology Co.,Ltd
Contact:+86-769-22181286
Address:Huanan Industial Park, Dongguan,China
Shanghai Taibao Pharmaceutical Technology Co., Ltd(expird)
Contact:021-52217366
Address:shanghai
Xi'an Unique Electronic and Chemical Co., Ltd.
Contact:+86-029-88238008
Address:1703# B BUILDING WEST ELECTRONIC ZONE, XI'AN, CHINA
Contact:
Address:ROOM 1715, No#345 Jin Xiang Road, Pudong District
Shangyu Sanhechemicals Co.,LTD.
Contact:86-0571-56696839
Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
Doi:10.1016/j.jorganchem.2014.06.012
(2014)Doi:10.1002/anie.201310944
(2014)Doi:10.1055/s-1994-25674
(1994)Doi:10.1021/jm00006a024
(1995)Doi:10.1002/cber.19971300508
(1997)Doi:10.1039/c4ra02420f
(2014)
