First total synthesis of fungerin an antifungal alkaloid from fusarium sp.

DOI: 10.1016/S0040-4039(98)01203-9

Source and publish data:

Tetrahedron Letters p. 5963 - 5964 (1998)

Update date:2022-08-05

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Authors:

Benhida, Rachid

Lezama, Ruth

Fourrey, Jean-Louis

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Article abstract of DOI:10.1016/S0040-4039(98)01203-9

The first total synthesis of fungerin 1, a new antifungal alkaloid, is described. Starting from a 4,5-diiodoimidazole derivative, the procedure involves regioselective prenylation and Heck type reaction steps to give 1 in high yield.

Full text of DOI:10.1016/S0040-4039(98)01203-9

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Product name:4-Iodo-1-methyl-5-(3-methyl-but-2-enyl)-1H-imidazole

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