Journal of Antibiotics p. 664 - 678 (2001)
Update date:2022-08-04
Topics:
Kashimura
Asaka
Misawa
Matsumoto
Morimoto
The novel 6-O-methyl tricyclic ketolides TE-802 and its analogs were synthesized by two successive cyclization reactions, 11,12-cyclic carbamate formation by intramolecular Michael addition and 9,11-diazaheptene ring construction by intramolecular dehydration reaction. These new tricyclic ketolides exhibited good in vitro antibacterial activity against not only erythromycin-susceptible strains but also erythromycin-resistant Staphylococcus aureus and Streptococcus pneumoniae, which are problematic pathogens of nosocomial and community-acquired respiratory tract infections, respectively.
View MoreShanghai Massive Chemical Technology Co., Ltd.
website:http://www.massivechem.com/
Contact:+86 21 34943721
Address:Room 435, 4th floor, Building 9, No. 2568 Gudai Road,Minhang District, Shanghai,
Contact:+86-27-87204219, +86-27-87215023
Address:2402, HuiGu Space-time Building, 8 Forest Road, East Lake Hi-Tech Development Zone
Contact:+86-571-87010026
Address:202, Zhenhua Road,
Shanghai Send Pharmaceutical Technology Co., Ltd.
website:http://www.shsendpharma.com
Contact:021-58088081, +8613585868794
Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China
ShangHai Original Economy-Trade Develop Co.,Ltd.,
Contact:86-21-68552131
Address:shanghai
Doi:10.1246/cl.1998.831
(1998)Doi:10.1016/S0040-4020(98)00668-1
(1998)Doi:10.1021/jm00339a006
(1963)Doi:10.1007/BF02495613
(1998)Doi:10.1016/S0957-4166(98)00261-4
(1998)Doi:10.1016/S0040-4020(98)00693-0
(1998)
