Journal of Antibiotics p. 664 - 678 (2001)
Update date:2022-08-04
Topics:
Kashimura
Asaka
Misawa
Matsumoto
Morimoto
The novel 6-O-methyl tricyclic ketolides TE-802 and its analogs were synthesized by two successive cyclization reactions, 11,12-cyclic carbamate formation by intramolecular Michael addition and 9,11-diazaheptene ring construction by intramolecular dehydration reaction. These new tricyclic ketolides exhibited good in vitro antibacterial activity against not only erythromycin-susceptible strains but also erythromycin-resistant Staphylococcus aureus and Streptococcus pneumoniae, which are problematic pathogens of nosocomial and community-acquired respiratory tract infections, respectively.
View MoreHubei Honch Pharmaceutical Co.,Ltd
Contact:86-713-7222018
Address:Li Shizhen Pharmaceutical Industry park, Qichun County, Hubei Province,China
Suzhou Sinosun Imp.&Exp. Corporation
website:http://www.szsinosun.com
Contact:+86-512-63488895,63488616
Address:No.758 East Jiangling Road Wujiang Economic & Technological Developmenty Zone Jiangsu China
Contact:+86 021-51698675
Address:1701, Jielong Plaza, No.618 Pingliang Rd, ShangHai,China
Contact:+86-519-86623222
Address:29F/D, 99 Yanling West Road, Changzhou, Jiangsu, China
SHIFANG SUHONG CHEMICAL CO.,LTD
Contact:+86-838-2224563
Address:Room 1207 Zongchen Sunshine No.128 Taishan South Road,Deyang City,Sichuan China
Doi:10.1246/cl.1998.831
(1998)Doi:10.1016/S0040-4020(98)00668-1
(1998)Doi:10.1021/jm00339a006
(1963)Doi:10.1007/BF02495613
(1998)Doi:10.1016/S0957-4166(98)00261-4
(1998)Doi:10.1016/S0040-4020(98)00693-0
(1998)
