Tetrahedron Letters p. 7211 - 7214 (1998)
Update date:2022-09-26
Topics:
East, Stephen P.
Joullie, Madeleine M.
A strained 14-membered cyclopeptide was prepared from the Garner aldehyde derived from D-serine. The key steps in the synthesis were the construction of the alkyl-aryl ether linkage via an S(N)Ar reaction involving 4-fluorobenzonitrile and the macrolactamization using a modification of the Schmidt protocol involving an activated pentafluorophenyl ester.
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Doi:10.1016/j.tetlet.2013.07.158
(2013)Doi:10.1016/S0968-0896(98)00094-7
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(2015)Doi:10.1021/ol015727m
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(2009)Doi:10.1016/S0040-4020(97)10014-X
(1997)
