Asymmetric synthesis of chiral 2-fluorinated 1,3-propanediols and its application to the preparation of monofluorinated chiral synthon

DOI: 10.1016/S0040-4039(98)01687-6

Source and publish data:

Tetrahedron Letters p. 7741 - 7744 (1998)

Update date:2022-07-30

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Authors:

Yokoyama, Hajime

Hyodo, Ryo

Nakada, Akiko

Yamaguchi, Seiji

Hirai, Yoshiro

Kometani, Tadashi

Goto, Michimasa

Shibata, Norio

Takeuchi, Yoshio

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Article abstract of DOI:10.1016/S0040-4039(98)01687-6

Asymmetric synthesis of optically active 2-fluorinated 1,3-propanediols was achieved by enzymatical resolution and applied to obtain a chiral monofluorinated synthon for lignan derivatives.

Full text of DOI:10.1016/S0040-4039(98)01687-6

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