A novel two-step preparation of enaminoketones by amination of α,β- unsaturated ketones with methoxyamine

Article abstract of DOI:10.1016/S0040-4039(98)01801-2

β-Methoxyaminoketones, derived from the addition of methoxyamine to 1,3-diaryl-2-propen-1-one, underwent base-induced β-elimination to furnish the corresponding enaminoketones in good to moderate yields. The reaction conditions and substituents on the substrates significantly influenced the selectivity in the production of enaminoketone and/or aziridineketone.