Tetrahedron Letters p. 7975 - 7978 (1998)
Update date:2022-08-05
Topics:
Vyle, Joseph S.
Williams, Nicholas H.
Grasby, Jane A.
Michaelis-Arbusov chemistry was used to prepare O,S-dialkyl 3'-O- nucleosidyl phosphorothiolate triesters in solution and attached to CPG. The support-bound nucleoside was utilised in the synthesis of a pentaribonucleotide that was fully deprotected on the support. Subsequent treatment with a buffered solution of iodine cleaved the RNA from the CPG with concomitant formation of a terminal 2',3'-cyclic phosphate.
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Doi:10.1021/jf9813485
(1999)Doi:10.1080/00304948.2020.1762457
(2020)Doi:10.1021/jo01264a062
(1969)Doi:10.1007/BF00760283
()Doi:10.1515/HC.2005.11.6.505
(2005)Doi:10.1246/bcsj.51.3391
(1978)