Bulletin of the Chemical Society of Japan p. 2387 - 2391 (1998)
Update date:2022-08-05
Topics:
Erian, Ayman Wahba
Abu-Shanab, Fathi Ali
The reaction of azine-thiones with ethyl chlorofluoroacetate afforded 2- fluorothienoazines. The latter underwent self-condensation and gave multi- fused heterocyclic compounds. A wide range of unique heterocycles could be obtained on treatment of 2-fluorothienoazines with nitrogen nucleophilic reagents. The reactivity of the pyrimidine-thiones towards a variety of electrophilic reagents was studied. Chemical and spectroscopic evidence of the newly synthesized compounds are described.
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