An efficient synthesis of tetrasubstituted imidazoles from N-(2-Oxo)- amides

DOI: 10.1016/S0040-4039(98)02058-9

Source and publish data:

Tetrahedron Letters p. 8939 - 8942 (1998)

Update date:2022-08-05

Topics:

Authors:

Claiborne, Christopher F.

Liverton, Nigel J.

Nguyen, Kevin T.

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Article abstract of DOI:10.1016/S0040-4039(98)02058-9

N-(2-Oxo)-amides were efficiently converted to tri- and tetra- substituted imidazoles under neutral reaction conditions upon treatment with neat ammonium trifluoroacetate.

Full text of DOI:10.1016/S0040-4039(98)02058-9

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