Structure-based design of peptidomimetic ligands of the Grb2-SH2 domain

DOI: 10.1016/S0960-894X(98)00513-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2865 - 2870 (1998)

Update date:2022-07-29

Topics:

Authors:

Schoepfer, Joseph

Gay, Brigitte

Caravatti, Giorgio

Garcia-Echeverria, Carlos

Fretz, Heinz

Rahuel, Joseph

Furet, Pascal

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00513-7

We have designed and synthesized a (3-aminomethyl-phenyl)-urea scaffold to mimic the X₊₁-Asn part of the minimal phosphopeptide sequence, Ac-pTyr- X₊₁-Asn-NH2, recognized by the Grb2SH2 domain. The resulting compounds show the same d

Full text of DOI:10.1016/S0960-894X(98)00513-7

Products guided by the article

Product name:4-oxo-4-(3-ureido-phenyl)-butyric acid

Cas No:218300-35-7

R&D Labs maybe for 218300-35-7

Changzhou Ansciep Chemical Co.,Ltd.

Contact:+86 519 8630 5871

Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
JIEJIE GROUP CO.,LTD.

Contact:+86 021-51698675

Address:1701, Jielong Plaza, No.618 Pingliang Rd, ShangHai,China
Oceachem Group Limited

website:http://www.oceanchem-group.com

Contact:86-536-8596048

Address:9th floor,Building B future Plaza, No.88.Fenghuang Street,Weifang,Shandong,China
SHANDONG CREDAGRI CHEMICAL CO., LTD.

Contact:+86-531-88872050

Address:ROOM 601A, BUILDING 2, SHUNTAI SQUARE, NO. 2000 SHUNHUA ROAD, HI-TECH DEVELOPMENT ZONE, JINAN, CHINA.
Zhejiang Kangfeng Chemical Co.,LTD.

Contact:+86-579-86709687

Address:Xueshizhai Industrial Zone, Weishan Town,Dongyang City, Zhejiang Province ,China

Relevant to this article

Structure-reactivity correlations in the dissociative hydrolysis of 2′,4′-dinitrophenyl 4-hydroxy-X-benzenesulfonates

Doi:10.1021/jo961024k
(1996)
Synthesis of 4-cyanophenyl and 4-nitrophenyl 1,5-dithio-L- and -D-arabinopyranosides possessing antithrombotic activity

Doi:10.1016/S0008-6215(98)00221-3
(1998)
Oxidation with selenium dioxide: The first report of solvent-selective steroidal aromatization, efficient access to 4β,7α-dihydroxy steroids, and syntheses of natural diaromatic ergosterols

Doi:10.1016/j.tet.2012.05.110
(2012)
The design, synthesis, and initial evaluation of benzophenone-containing peptides as potential photoaffinity labels of oligosaccharyltransferase

Doi:10.1016/S0968-0896(98)00135-7
(1998)
Formylation of electron-rich aromatic rings mediated by dichloromethyl methyl ether and TiCl₄: Scope and limitations

Doi:10.3390/molecules20045409
(2015)
Synthesis of triamidoamine ligands of the type (arylNHCH₂CH₂)₃N and molybdenum and tungsten complexes that contain an [(arylNCH₂CH₂)₃N]³-ligand

Doi:10.1021/ic001122v
(2001)

Article Doi