N-Boc-3-trichloromethyloxaziridine: A new, powerful reagent for electrophilic amination

DOI: 10.1016/S0040-4039(98)01983-2

Source and publish data:

Tetrahedron Letters p. 8845 - 8848 (1998)

Update date:2022-08-02

Topics:

Authors:

Vidal, Joelle

Hannachi, Jean-Christophe

Hourdin, Gwenaelle

Mulatier, Jean-Christophe

Collet, Andre

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Article abstract of DOI:10.1016/S0040-4039(98)01983-2

The aza-Wittig reaction of Ph₃P=N-Boc with chloral, followed by the oxone oxidation of the resulting imine, afforded N-Boc-3- trichloromethyloxaziridine in excellent yield. This new oxaziridine proved to be a powerful electrophilic amination reagent.

Full text of DOI:10.1016/S0040-4039(98)01983-2

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