Synthetic studies toward potent cytotoxic agents amphidinolides: Synthesis of the C1-C18 moiety of amphidinolides G, H and L

DOI: 10.1016/S0040-4039(98)02009-7

Source and publish data:

Tetrahedron Letters p. 9109 - 9112 (1998)

Update date:2022-08-03

Topics:

Authors:

Chakraborty

Suresh Suresh

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Article abstract of DOI:10.1016/S0040-4039(98)02009-7

Stereoselective synthesis of the (8S, 9S, 11R, 16S)-C₁-C₁₈ segment 1 of amphidinolides G, H and L, bearing the unique trisubstituted 's-cis-1,3- diene' moiety (C(28(29))=C₁₃-C₁₄=C₁₅), has been achieved for the first time following a highly efficient convergent strategy.

Full text of DOI:10.1016/S0040-4039(98)02009-7

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