Tetrahedron Letters p. 8755 - 8758 (1998)
Update date:2022-08-03
Topics:
Donohoe, Timothy J.
Blades, Kevin
Helliwell, Madeleine
Waring, Michael J.
Newcombe, Nicholas J.
The first synthesis of (+)-pericosine B is described; this takes seven steps and proceeds in 10% overall yield. The key step in our work is a hydrogen-bonding controlled contra-steric dihydroxylation reaction using osmium tetroxide and an amine promoter. The absolute stereochemistry of the natural product was deduced from the known absolute stereochemistry of our starting material and moreover, the relative and absolute stereochemistry of our synthetic material was determined unambiguously from an X-ray crystal structure of an advanced intermediate.
View MoreJIANGXI XINXIN CHEMICAL CO., LTD.
Contact:86-15957176628
Address:INDUSTRY ROAD 1, INDUSTRIAL PARK, HEKOU TOWN,YANSHAN COUNTY, JIANGXI PROVINCE, CHINA
Zhengzhou Gecko Scientific Inc.
Contact:0371-88884176
Address:56 Hongzhuan Road, Zhengzhou, China
Changzhou Ruiping Chemical Co., Ltd
website:http://www.wishchem.com
Contact:+86-519-82324280
Address:No.288-1 Huacheng Road, Jintan
Wuhan Chemwish Technology Co., Ltd
website:http://www.chemwish.com/
Contact:+86-27-67849912
Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei,P.R. China
Zibo Fuxi'er Chemical Co.,Ltd (Shanxian Fuxi'er Chemical Co.,Ltd)
Contact:+86-533-2091422
Address:Eastern 4 on the 3th Road ,Liangxiang Industrial Park, Zibo city ,Shandong,China
Doi:10.1016/j.bmcl.2010.06.086
(2010)Doi:10.1021/jo2019762
(2012)Doi:10.1016/j.tetlet.2010.06.070
(2010)Doi:10.1021/ja00181a036
(1990)Doi:10.1007/BF03246216
(2011)Doi:10.1007/s11172-005-0203-x
(2004)