Intramolecular cycloadditions of nittones derived from 1-allyl-2- pyrrolecarbaldehyde as a route to racemic and enantiopure pyrrolizidines and indolizidines

DOI: 10.1021/jo9810415

Source and publish data:

Journal of Organic Chemistry p. 9279 - 9284 (1998)

Update date:2022-09-26

Topics:

Authors:

Arnone, Alberto

Broggini, Gianluigi

Passarella, Daniele

Terraneo, Alberto

Zecchi, Gaetano

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo9810415

A version of the intramolecular nitrone cycloaddition strategy, using 2- pyrrolecarbaldehyde as starting material, has been developed to synthesize new pyrrolizidines and indolizidines structurally related to biologically active alkaloids. The target molecules have been accessible in racemic as well as enantiopure form.

Full text of DOI:10.1021/jo9810415

Products guided by the article

Product name:(+)-(αR,1R,4S)-2-(α-phenylethyl)-1,2,4,5-tetrahydro-1.4-methanopyrrolo<2,1-d><1,2,5>oxadiazepine

Cas No:219666-82-7

R&D Labs maybe for 219666-82-7

Yuan Shi(SuQian)Biotechnology Co.,Ltd

website:http://www.yuanshibio.com

Contact:+86-527-84226672

Address:jiangsu suqian
Suzhou SuKaiLu Chemical Technology Co., Ltd.

Contact:+86-512-62766020

Address:Floor 4, Building 1, Xinyi Pharmaceutical Valley Wisdom Industrial Park, 415 Changyang Street, Suzhou Industrial Park, Jiangsu Province
SHANDONG QINGYUNCHANGXIN CHEMICAL SCIENCE-TECH CO.,LTD

Contact:86-21-60560171

Address:1689Donghuan Rade,Qingyun County, Dezhou City, Shandong,China
Shijiazhuang Sdyano Fine Chemical Co., Ltd

Contact:+86-311-89830448

Address:NO.48 Ta Nan Road,Yuhua District,Shijiazhuang,Hebei,China
JiangXi Keyuan Biopharma Co., LTD.

Contact:+86-563-6833666

Address:Guangde Fine Chemical Zone, Anhui Province, China

Relevant to this article

Enantioselective Synthesis of α,β,α′-Trisubstituted Cyclic Ethers

Doi:10.1021/jo981188w
(1998)
Application of the β-azidonation reaction to the synthesis of the antitumor alkaloid (+)-pancratistatin

Doi:10.1016/S0040-4020(98)00975-2
(1998)
Structure-activity relationships and optimisation of the selective MDR modulator 2-(3,4-dimethoxyphenyl)-5-(9-fluorenylamino)-2-(methylethyl) pentanenitrile and its N-methyl derivative

Doi:10.1016/S0968-0896(01)00191-2
(2001)
Design, synthesis and evaluation of novel 2,5,6-trisubstituted benzimidazoles targeting FtsZ as antitubercular agents

Doi:10.1016/j.bmc.2014.03.035
(2014)
The effect of protonation on the spectroscopic and redox properties of a series of ferrocenoyl derivatives

Doi:10.1039/a807453d
(1999)
Iron-mediated direct suzuki-miyaura reaction: A new method for the ortho -arylation of pyrrole and pyridine

Doi:10.1021/ol100838m
(2010)

Article Doi