Oligonucleotides bearing 5-formyl-2 '-O-methyluridine: Preference in binding affinity to the NF-κB (p50)2 homo- and p50/p65 heterodimers

Article abstract of DOI:10.1016/S0960-894X(98)00584-8

5-Formyl-2'-O-methyluridine was incorporated into the various positions of oligonucleotide 26-mers containing the NF-κB binding sequence. Some of them showed binding selectivity toward the homo- and heterodimers of subunits of NF-κB.