A new series of C3-aza carbocyclic influenza neuraminidase inhibitors: synthesis and inhibitory activity.

DOI: 10.1016/S0960-894X(98)00587-3

Source and publish data:

Bioorganic and medicinal chemistry letters p. 3321 - 3324 (1998)

Update date:2022-08-03

Topics:

Authors:

Lew Lew

Mendel Mendel

Escarpe Escarpe

Chen Chen

Laver Laver

Graves Graves

Kim Kim

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00587-3

The synthesis and influenza neuraminidase inhibitory activity of a new series of C3-aza carbocyclic neuraminidase inhibitors are described. Analogues 3c and 3j, bearing a 3-pentyl group, exhibit influenza A inhibitory activities comparable to that of 1.

Full text of DOI:10.1016/S0960-894X(98)00587-3

Products guided by the article

Product name:(3R,4S,5S)-4-Acetylamino-3-amino-5-tert-butoxycarbonylamino-cyclohex-1-enecarboxylic acid ethyl ester

Cas No:220479-06-1

R&D Labs maybe for 220479-06-1

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

website:http://www.jlpharms.com

Contact:86-571-86982636

Address:Rm A606, Fuyi Center, jianqiao street
Sarchem Laboratories, Inc.

Contact:732.938.2777

Address:5012 Industrial Road Farmingdale, NJ 07727
Changsha Botaniex Inc.

Contact:(86) 731 88718666

Address:Room 1222, Unit 4, Building B, Shangcheng, No.47, Kaiyuan East Road.
Taixing Shenfeng Chemical Co., Ltd.

Contact:+86-523-87117033, 87117666

Address:4# Yinsanlu, Huangqiao town, Taixing, Jiangsu, China.
JIEJIE GROUP CO.,LTD.

Contact:+86 021-51698675

Address:1701, Jielong Plaza, No.618 Pingliang Rd, ShangHai,China

Relevant to this article

Doi:10.1021/ja01534a058
(1958)
Regioselective synthesis of 6-alkynyl-6-deoxy and pseudo-C- disaccharides derivatives of mannofuranose via a 5,6-cyclic sulfate

Doi:10.1055/s-1999-3389
(1999)
One- and two-electron oxidative pathways leading to cyclopropane-containing oxidized porphyrinogens and C-C-coupled porphyrinogens from alkali cation- and transition metal-meso-octaethylporphyrinogen complexes

Doi:10.1021/ja982178f
(1999)
A formal synthesis of pumiliotoxin 251D, via a highly diastereoselective addition of a titanium homoenolate to an L-proline derivative

Doi:10.1021/jo9820972
(1999)
Transformation of a monoterpene ketone, (R)-(+)-pulegone, a potent hepatotoxin, in Mucor piriformis

Doi:10.1021/jf980164n
(1999)
An organocatalyst from renewable materials for the synthesis of coumarins and chromenes: Three-component reaction and multigram scale synthesis

Doi:10.1039/c4ra00673a
(2014)

Article Doi