A new series of C3-aza carbocyclic influenza neuraminidase inhibitors: synthesis and inhibitory activity.

DOI: 10.1016/S0960-894X(98)00587-3

Source and publish data:

Bioorganic and medicinal chemistry letters p. 3321 - 3324 (1998)

Update date:2022-08-03

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Authors:

Lew Lew

Mendel Mendel

Escarpe Escarpe

Chen Chen

Laver Laver

Graves Graves

Kim Kim

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Article abstract of DOI:10.1016/S0960-894X(98)00587-3

The synthesis and influenza neuraminidase inhibitory activity of a new series of C3-aza carbocyclic neuraminidase inhibitors are described. Analogues 3c and 3j, bearing a 3-pentyl group, exhibit influenza A inhibitory activities comparable to that of 1.

Full text of DOI:10.1016/S0960-894X(98)00587-3

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