Tobramycin-EDTA conjugate: A noninnocent affinity-cleaving reagent

DOI: 10.1016/S0960-894X(98)00663-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 3665 - 3670 (1998)

Update date:2022-08-05

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Authors:

Wang, Hai

Tor, Yitzhak

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Article abstract of DOI:10.1016/S0960-894X(98)00663-5

The design, synthesis, and ribozyme inhibitory activity of a novel EDTA- aminoglycoside conjugate are reported. This affinity cleaving reagent is a noninnocent RNA binder: its RNA affinity, judged by its ability to inhibit the hammerhead ribozyme HH16, is

Full text of DOI:10.1016/S0960-894X(98)00663-5

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