Tetrahedron Letters p. 2049 - 2052 (1999)
Update date:2022-08-04
Topics:
Grohar, Patrick J.
Chow, Christine S.
An alternative synthesis of the modified RNA nucleoside pseudouridine is reported. This procedure employs coupling of an iodinated pyrimidine and a suitably protected lactone. The resulting hemiacetal is reduced and deprotected to yield pseudouridine.
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