A novel donor for stereoselective α-Sialylation; efficient synthesis of an α(2-8)-linked bis-sialic acid unit

Article abstract of DOI:10.1016/S0040-4039(99)00175-6

The novel sialyl donor methyl [ethyl 5-(N,N-diacetyl)-4,7,8,9-tetra-O- acetyl-2-thio-3-thiophenyl-2,3,5-trideoxy-D-erythro-α-L-gluco-2- nonulopyranosid]onate (2) was synthesized by N-acetylation of the corresponding 5-acetamido compound 1. α-Sialylation o