Tetrahedron p. 1755 - 1762 (1999)
Update date:2022-07-30
Topics:
Martin-Santamarisa, Sonsoles
Espada, Modesta
Avendano, Carmen
(4S)-2,4-Dimethyl-2,4-dihydro-(1H)-pyrazino[2,1-b]quinazoline-3,6-dione was converted into to the cis-tosylate 2, whose reactivity as an electrophilic glycine template is discussed. It was found that this compound does not give direct S(N)2-type displacement of the tosyloxy group. However, the 1-hydoxy derivative 3, obtained by hydrolysis of 2 with net retention of the stereochemistry, and its 1-methoxy derivative 4a are electrophilic glycine templates.
View MoreHebei DaPeng Pharm & Chem Co., Ltd.
Contact:86-317-7298678,0576-88861898 88861908
Address:West Songmen Village, East Songmen Town, Wuqiao, Cangzhou, Hebei ,China
Contact:+86-571-28186845
Address:Room 1224,Eastcom Mansion,398 Wensan Road,Hangzhou,310013 China
Nanjing Qirui Material Co., Ltd.
Contact:+86-25-52320053
Address:F4-5, #17 Building, Chuang Yi Yuan, No.6 Guanghua East Street, Nanjing, 210007 P.R.China
Henan Techway Chemical Co.,Ltd.
website:http://www.techwaychem.com
Contact:+86-371-66380080
Address:No.27 Shunhe Road,
Nanjing distinctions Medical Technology Co., Ltd.(expird)
Contact:+86-15996203785 13914714059
Address:nanjing,jiangsu , China
Doi:10.1016/S0960-894X(00)00695-8
(2001)Doi:10.1021/ja01511a039
(1951)Doi:10.1016/S0040-4039(99)00006-4
(1999)Doi:10.1016/S0968-0896(98)00225-9
(1999)Doi:10.1016/S0031-9422(00)85451-5
(1969)Doi:10.1016/j.bmcl.2004.03.094
(2004)
