Synthesis of N-substituted azetidin-3-ones

Article abstract of DOI:10.1080/00397919908086047

Addition of RC(O)Cl (R = OEt, Me, or Ph) across the highly strained N- C(3) σ-bond in 3-bromomethyl-1-azabicyclo[1.1.0]butane (1) afforded the corresponding N-acyl-3-bromomethyl-3-chloroazetidines (2a-2c, respectively). Subsequent zinc promoted eliminativ

Full text of DOI:10.1080/00397919908086047

This article was downloaded by: [University of Glasgow]
On: 10 May 2013, At: 07:50
Publisher: Taylor & Francis
Informa Ltd Registered in England and Wales Registered Number: 1072954
Registered office: Mortimer House, 37-41 Mortimer Street, London W1T 3JH,
UK
Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
Publication details, including instructions for
authors and subscription information:
http://www.tandfonline.com/loi/lsyc20
Synthesis of N-Substituted
Azetidin-3-ones
Alan P. Marchand a & Arokiasamy Devasagayaraj a
a Department of Chemistry, University of North
Texas, Denton, Texas, 76203-5070
Published online: 17 Sep 2007.
To cite this article: Alan P. Marchand & Arokiasamy Devasagayaraj (1999): Synthesis
of N-Substituted Azetidin-3-ones, Synthetic Communications: An International Journal
for Rapid Communication of Synthetic Organic Chemistry, 29:5, 885-890
To link to this article: http://dx.doi.org/10.1080/00397919908086047
PLEASE SCROLL DOWN FOR ARTICLE
Full terms and conditions of use: http://www.tandfonline.com/page/terms-
and-conditions
This article may be used for research, teaching, and private study purposes.
Any substantial or systematic reproduction, redistribution, reselling, loan,
sub-licensing, systematic supply, or distribution in any form to anyone is
expressly forbidden.
The publisher does not give any warranty express or implied or make any
representation that the contents will be complete or accurate or up to
date. The accuracy of any instructions, formulae, and drug doses should be
independently verified with primary sources. The publisher shall not be liable
for any loss, actions, claims, proceedings, demand, or costs or damages

whatsoever or howsoever caused arising directly or indirectly in connection
with or arising out of the use of this material.