Synthesis and antibacterial activity of 6-O-heteroarylcarbamoyl-11,12- lactoketolides

DOI: 10.1016/j.bmcl.2005.12.097

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1929 - 1933 (2006)

Update date:2022-08-05

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Authors:

Grant, Eugene B.

Guiadeen, Deodialsingh

Abbanat, Darren

Foleno, Barbara D.

Bush, Karen

MacIelag, Mark J.

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Article abstract of DOI:10.1016/j.bmcl.2005.12.097

A new series of erythromycin A derivatives, the 6-O-heteroarylcarbamoyl-11, 12-lactoketolides, with activity against macrolide-resistant streptococci, are described. Structurally, these macrolide antibiotics are characterized by a heteroaryl side chain at

Full text of DOI:10.1016/j.bmcl.2005.12.097

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