The macrocyclic domain of phorboxazole A. A stereoselective synthesis of the C1-C32 macrolactone

DOI: 10.1016/S0040-4039(99)00210-5

Source and publish data:

Tetrahedron Letters p. 2291 - 2294 (1999)

Update date:2022-08-05

Topics:

Authors:

Williams, David R.

Clark, Michael P.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)00210-5

A stereoselective synthesis of the C₁-C₃₂ macrocyclic domain of phorboxazole A is described. Key steps have examined the convergent linkage of two major components for the formation of the C₁₉-C₂₀ (E)-alkene, and the subsequent intramolecular (Z)-olefination at C₂-C₃ for ring closure of the macrocycle.

Full text of DOI:10.1016/S0040-4039(99)00210-5

Products guided by the article

Product name:2,2-Dimethyl-propionic acid 2-((2R,6R)-6-{(2R,4R,6R)-4-(tert-butyl-diphenyl-silanyloxy)-6-[2-(1-methyl-1H-imidazole-2-sulfonylmethyl)-oxazol-4-yl]-tetrahydro-pyran-2-ylmethyl}-4-methylene-tetrahydro-pyran-2-yl)-ethyl ester

Cas No:224575-48-8

R&D Labs maybe for 224575-48-8

Shanghai Yuantai Chemical Products Co., Ltd

Contact:021--66129803

Address:Chengyin Road,Shanghai,China
Jiangsu Allyrise Pharmaceutical Co., Ltd.(expird)

Contact:+86-523-86818997

Address:Taizhou,Jiangsu Province,CHINA
Chengdu Cogon Bio-tech Co., Ltd.

Contact:86-28-85171192

Address:NO.52.YongFeng Rd. Chengdu,610041,P.R.China.
Ceresking Ecology & Technology co.,ltd

Contact:86 22 66218397

Address:Room 1613, Zheshang Mansion, No. 1988, Yingbin Avenue, Binhai New District, Tianjin,China.
Watson International Ltd

Contact:+44 (0)2036089360-31

Address:Chanceryhouse,Chancery Lan

Relevant to this article

Transannular Interactions in Tetrafluoro[2.2]paracyclophane

Doi:10.1021/ja01035a054
(1969)
Trans-Diaquabis(benzoato-O)bis(nicotin-amide-N¹)cobalt(II)

Doi:10.1107/S0108270199000153
(1999)
Glycosyl phosphatidylinositol (GPI) anchor synthesis based on versatile building blocks - Total synthesis of a GPI anchor of yeast

Doi:10.1002/(SICI)1099-0690(199905)1999:5<1153::AID-EJOC1153>3.0.CO;2-S
(1999)
Chemical modifications and structure activity studies of ziracin and related everninomicin antibiotics

Doi:10.1016/S0960-894X(99)00163-8
(1999)
SYNTHESIS OF THE FOUR DL-PAIRS OF 2-AMINO-3-PHENYLNORBORNANE-2-CARBOXYLIC ACIDS

Doi:10.1016/S0040-4020(01)89251-6
(1989)
Suzuki-Miyaura reactions of N-protected tribromopyrazoles. Efficient and site-selective synthesis of 3,4,5-triaryl-pyrazoles, 3,5-diaryl-4-bromopyrazoles and 5-aryl-3,4-dibromopyrazoles

Doi:10.1016/j.tet.2011.05.036
(2011)

Article Doi