A facile synthesis of 3-aryl-substituted-benzothiophenes via a Lewis acid mediated cyclization of 2-arylthio-acetophenones

DOI: 10.1016/S0040-4039(99)00392-5

Source and publish data:

Tetrahedron Letters p. 2909 - 2912 (1999)

Update date:2022-08-03

Topics:

Authors:

Kim, Seongkon

Yang, Jane

DiNinno, Frank

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Article abstract of DOI:10.1016/S0040-4039(99)00392-5

The boron trifluoride-etherate mediated cyclization of 2-arylthio- ketones 1a-h at ambient temperature gave 3-aryl-substituted benzothiophenes 2a-h in excellent yield. None of the rearranged 2-aryl-substituted benzothiophenes were observed.

Full text of DOI:10.1016/S0040-4039(99)00392-5

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