Chemical and Pharmaceutical Bulletin p. 563 - 568 (1999)
Update date:2022-09-26
Topics:
Ikeda, Kiyoshi
Miyajima, Keisuke
Maruyama, Yasufumi
Achiwa, Kazuo
Conjugates 6 and 7 of cancer peptide antigen with N-tetradecanoyl L- serine-β-alanine-containing D-glucosamine derivative structurally related to lipid A as an immunoadjuvant were synthesized for the development of totally synthetic vaccines against cancers. The mitogenic activities of compounds 6 and 7 were stronger than that of lipid A analog 3.
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