The development of solid phase protocols for a backbone amide linker and its application to the Boc-based assembly of linear peptides

Article abstract of DOI:10.1016/S0040-4039(99)01473-2

Herein, we report on the solid phase synthesis of a backbone amide linker. The key step is the acylation of a secondary amide in quantitative yield. To show the application of this methodology we synthesised linear peptides CCK (25-33) and ACP (64-73) usi