Synthesis and some reactions of 4-aroyl-6-aryl pyridazin-3(2H)-thiones

Article abstract of DOI:10.1080/10426509808029669

4-Aroyl-3-chloro-6-arylpyridazines^[1] (1) react with thiourea to give 4aroyl-6-arylpyridazin-3 (2H)-thiones (2) respectively^[2-7]. The compounds 2 reacted with dimethyl sulphate, hydrazine hydrate and hydroxylamine hydrochloride to give 4-aroyl-6-aryl-3-methylthiopyridazines 5, pyrazolinopyridazines 7 and isoxazolopyridazine 8, respectively. The compounds 2a-c reacted in alkaline ammonium hydroxide solution with sodium hypochlorite solution to give the isothiazolopyridazines 10a-c.

Full text of DOI:10.1080/10426509808029669

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Phosphorus, Sulfur, and Silicon
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SYNTHESIS AND SOME
REACTIONS OF 4-AROYL-6-ARYL
PYRIDAZIN-3(2H)-THIONES
M. Fekry Ismail a , O. E. Mustafa a , S. A. Emara a ,
H. A. Y. Derbala a & H. A. Sallam a
a Chemistry Department, Faculty of Science , Ain
Shams University Abbassia , Cairo, Egypt
Published online: 24 Sep 2006.
To cite this article: M. Fekry Ismail , O. E. Mustafa , S. A. Emara , H. A. Y. Derbala
& H. A. Sallam (1998) SYNTHESIS AND SOME REACTIONS OF 4-AROYL-6-ARYL
PYRIDAZIN-3(2H)-THIONES, Phosphorus, Sulfur, and Silicon and the Related Elements,
142:1, 93-99, DOI: 10.1080/10426509808029669
To link to this article: http://dx.doi.org/10.1080/10426509808029669
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