An enantiocontrolled synthesis of the masked taxol C-13 side chain, oxazoline carboxylic acid

DOI: 10.1016/S0040-4039(99)00577-8

Source and publish data:

Tetrahedron Letters p. 3581 - 3582 (1999)

Update date:2022-08-04

Topics:

Authors:

Kang, Sung Ho

Kim, Cheol Min

Youn, Joo-Hack

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Article abstract of DOI:10.1016/S0040-4039(99)00577-8

Oxazoline carboxylic acid 6 as the taxol side chain precursor has been efficiently synthesized via the intramolecular iodoamidation of allylic trichloroacetimidate derived from trans-olefinic diol 1.

Full text of DOI:10.1016/S0040-4039(99)00577-8

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Product name:2,2,2-Trichloro-acetimidic acid (4S,5S,6R)-5-iodo-4-phenyl-2-trichloromethyl-5,6-dihydro-4H-[1,3]oxazin-6-ylmethyl ester

Cas No:229648-89-9

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