An expeditious synthesis of substituted and annelated pyrido[2,3- b]indoles

Article abstract of DOI:10.1016/S0040-4039(99)00530-4

An efficient and versatile synthesis of substituted and annelated pyrido[2,3-b]indoles (α-carboline) involving conjugate displacement on α- oxoketene dithioacetals by 1-methyl-2-oxoindole enolate anion and subsequent cyclization of the adducts in the presence of ammonium acetate has been described.