(E)-1,2-bis(5-aryl-1,3,4-oxadiazol-2-yl)ethenes

Article abstract of DOI:10.1055/s-1999-3511

A series of (E)-1,2-bis(1,3,4-oxadiazol-2-yl)ethenes with a variety of aromatic substituents in the 5-positions of the heterocycles was prepared by acylation of the corresponding tetrazoles with fumaryl chloride and subsequent thermal ring transformation. The modified Huisgen reaction renders a new pathway to 3-(1,3,4-oxadiazol-2-yl)propenoic acids and subsequently to the title compounds with different substituents.