Synthesis and antiviral activity of D- and L-isodideoxy nucleosides with exocyclic methylene

Article abstract of DOI:10.1080/15257779908041531

Novel D- and L-isodideoxynucleosides were synthesized starting from D- and Lxylose and evaluated for antiviral activities against HIV-1, HSV-1, HSV- 2, HBV and HCMV, respectively.

Full text of DOI:10.1080/15257779908041531

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Nucleosides and Nucleotides
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Synthesis and Antiviral Activity of D- and
L-Isodideoxy Nucleosides with Exocyclic
Methylene
Lak Shin Jeong a , Su Jeong Yoo a , Hyung Ryong Moon a , Moon Woo
Chun b & Chong-Kyo Lee c
a Laboratory of Medicinal Chemistry , College of Pharmacy, Ewha
Womans University , Seoul, 120-750, Korea
b College of Pharmacy, Seoul National University , Seoul, 151-742,
Korea
c Pharmaceutical Screening Center , Korea Research Institute of
Chemical Technology , Daejon, 305-606, Korea
Published online: 04 Oct 2006.
To cite this article: Lak Shin Jeong , Su Jeong Yoo , Hyung Ryong Moon , Moon Woo Chun & Chong-
Kyo Lee (1999) Synthesis and Antiviral Activity of D- and L-Isodideoxy Nucleosides with Exocyclic
Methylene, Nucleosides and Nucleotides, 18:4-5, 655-656, DOI: 10.1080/15257779908041531
To link to this article: http://dx.doi.org/10.1080/15257779908041531
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