The enantioselective total synthesis of the antitumor macrolide natural product rhizoxin D

DOI: 10.1016/S0040-4039(99)00731-5

Source and publish data:

Tetrahedron Letters p. 4145 - 4148 (1999)

Update date:2022-08-04

Topics:

Authors:

Lafontaine, Jennifer A.

Provencal, David P.

Gardelli, Cristina

Leahy, James W.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)00731-5

A convergent, enantioselective total synthesis of rhizoxin D (didesepoxy-rhizoxin), a potent antitumor natural product, was achieved via three critical olefinations, including a Horner-Emmons macrocyclization.

Full text of DOI:10.1016/S0040-4039(99)00731-5

Products guided by the article

Product name:(2E,4S,6S,7S,9E,11E,13E)-1-[(t-butyldimethylsilyl)oxy]-6-hydroxy-3,7,9,13-tetramethyl-14-(2'-methyl-4'-oxazolyl)-4-[(triisopropylsilyl)oxy]-2,9,11,13-tetradecatetraen-8-one

Cas No:237735-30-7

R&D Labs maybe for 237735-30-7

Zhengzhou Yuanli Biological Technology Co., Ltd.

Contact:+86-371-67897870/67897895

Address:No. 38, Qingyang Street, Zhengzhou, Henan, China
SJZ THLD IMP & EXP CO LTD

website:http://www.truewingroup.com

Contact:86-311-66699812

Address:NO.600 ZHONGSHAN EAST ROAD SHIJIAZHUANG
KODI CHEMICAL CO., LTD

Contact:021

Address:Pudong
Deltachem(QingDao)Co.,Ltd.

Contact:+8618766299236

Address:ROOM808, BUILDING2,NO.230 SHEN ZHEN ROAD, LAOSHAN DISTRICT
Lianyungang Ningkang Chemical Co., Ltd

Contact:.+86-518-88588008

Address:http://www.chemnk.com

Relevant to this article

An efficient synthesis of pyrrolo[1,2-a]quinazoline derivatives in ionic liquid catalyzed by iodine

Doi:10.1002/jhet.1116
(2014)
Doi:10.1039/j39690001868
(1969)
Synthesis and pharmacological action of 3-amino-2,1-benzisothiazoles.

Doi:10.1021/jm00328a024
(1965)
Synthesis of 1,2-Disubstituted Cyclopentadienes from Alkynes Using a Catalytic Haloallylation/Cross-Coupling/Metathesis Relay

Doi:10.1021/acs.orglett.6b01682
(2016)
Bi(TFA)₃-[nbp]FeCl₄: a new, efficient and reusable promoter system for the synthesis of 4(3H)-quinazolinone derivatives

Doi:10.1016/j.tetlet.2006.03.079
(2006)
Efficient Intramolecular Glycosylation Supported by a Rigid Spacer

Doi:10.1021/jo990132e
(1999)

Article Doi