Design, synthesis and acaricidal activities of Cyflumetofen analogues based on carbon-silicon isosteric replacement

Article abstract of DOI:10.1016/j.bmc.2020.115509

The application of a carbon-silicon bioisosteric replacement strategy to find new acaricides with improved properties led to the discovery of Sila-Cyflumetofen 6B, a novel and highly potent acaricide. The essential t-butyl group in the beta-ketonitrile ac