
Tetrahedron Letters p. 5333 - 5336 (1999)
Update date:2022-07-30
Topics:
Kim, B. Moon
Cho, Jong Hyun
Diphenylsilydiethylene- (DPSide-) group has been developed as a new primary amine protecting group. The new protecting group exhibits novel orthogonality against other commonly used amine-protecting groups and excellent chemoselectivity for unbranched α-amino acid esters. Removal of this protecting group was effected under mild fluoride-based cleavage conditions.
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Doi:10.1039/b920058d
(2010)Doi:10.1002/chem.201203693
(2013)Doi:10.1021/ja01035a027
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(1999)