Biological and Pharmaceutical Bulletin p. 590 - 597 (1999)
Update date:2022-08-04
Topics:
Yamamoto, Fumihiko
Oka, Hidenobu
Antoku, Shigetoshi
Ichiya, Yu-Ichi
Masuda, Kouji
Maeda, Minoru
In order to develop new imaging markers for brain hypoxia, two lipophilic nitroimidazoles, 1-(3-fluoropropyl)-2-nitroimidazole (FPN) and 1- (8-fluorooctyl)-2-nitroimidazole (FON) were synthesized and labeled with fluorine-18. The octanol/water partition c
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