Bioorganic and Medicinal Chemistry Letters p. 1481 - 1486 (1999)
Update date:2022-08-05
Topics:
Vara Prasad
Boyer, Fred E.
Domagala, John M.
Ellsworth, Edmund L.
Gajda, Christopher
Hagen, Susan E.
Markoski, Larry J.
Tait, Bradley D.
Lunney, Elizabeth A.
Tummino, Peter J.
Ferguson, Donna
Holler, Tod
Hupe, Donald
Nouhan, Carolyn
Gracheck, Stephen J.
VanderRoest, Steven
Saunders, James
Iyer, Krishna
Sinz, Michael
Brodfuehrer, Joanne
Dihydropyran-2-ones possessing amino and carboxamide functionalities on 3-SPh (2-tert-butyl, 5-methyl) ring were synthesized and evaluated for their antiviral activities. Both the enantiomers of inhibitor 15 were synthesized. The in vitro resistance profi
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