Tetrahedron Letters p. 4527 - 4530 (1999)
Update date:2022-08-05
Topics:
Wolbers, Peter
Misske, Andrea M.
Hoffmann, H. Martin R.
Two approaches towards an enantiopure C15-C26 segment of the phorboxazoles starting from the corresponding C20-C26 aldehyde are presented. A variety of functionalized oxazoles have been synthesized via the rhodium(II) acetate catalyzed cycloaddition of dimethyl diazomalonate to substituted nitriles.
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