IMDA/retro-Mannich approach to cis-perhydroquinoline Lycopodium alkaloids: Asymmetric synthesis of (+)-luciduline

DOI: 10.1021/ol990028j

Source and publish data:

Organic Letters p. 229 - 231 (1999)

Update date:2022-08-03

Topics:

Authors:

Comins, Daniel L.

Brooks, Clinton A.

Al-Awar, Rima S.

Goehring, R. Richard

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Article abstract of DOI:10.1021/ol990028j

(equation presented) The first chiral auxiliary mediated asymmetric synthesis of the naturally occurring Lycopodium alkaloid (+)-luciduline has been accomplished. Key steps include an IMDA reaction of a chiral dihydropyridine, a subsequent retro-Mannich r

Full text of DOI:10.1021/ol990028j

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