Heterocycles p. 1543 - 1561 (1999)
Update date:2022-07-30
Topics:
Mitsos, Christos
Zografos, Alexandros
Igglessi-Markopoulou, Olga
A general protocol for the construction of 4-hydroxyquinolin-2-ones is described. Benzoxazinones react with the anion of active methylene compounds to produce the functionalized C-acylation compounds in very good yields. These key intermediates are cyclized to the desired quinolinones (25-40) under basic conditions. Spectral data and physical characteristics for all compounds are reported.
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Doi:10.1007/BF02496186
(1999)Doi:10.1002/oms.1210020608
(1969)Doi:10.1016/S0022-328X(99)00206-5
(1999)Doi:10.1021/j100323a070
(1988)Doi:10.1039/b000119h
(2000)Doi:10.1016/j.poly.2020.114934
(2021)
