Tetrahedron Letters p. 5155 - 5159 (1999)
Update date:2022-09-26
Topics:
Bradley, David A.
Godfrey, Alexander G.
Schmid, Christopher R.
Difunctionalized benzo[b]thiophene intermediates are prepared which allow fully independent elaboration of the 2-aryl position or the tether position of benzo[b]thiophene-based selective estrogen receptor modulators (SERMs). Two concise syntheses of the SERM raloxifene (Evista) are presented.
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Doi:10.1055/s-0040-1707196
(2020)Doi:10.1016/S0040-4020(99)00532-3
(1999)Doi:10.1039/P19840002573
(1984)Doi:10.1021/jo01257a052
(1969)Doi:10.1002/hlca.19690520845
(1969)Doi:10.1021/ja990219h
(1999)