Bioorganic and Medicinal Chemistry Letters p. 1559 - 1562 (1999)
Update date:2022-08-04
Topics:
Hsiao, Yi
Wells, Kenneth M.
Yang, Chunhua
Jensen, Mark S.
Chung, John Y.L.
Yasuda, Nobuyoshi
Hughes, David L.
Crystalline 1β-methyl-2-formyl carbapenem pNB esters were prepared by osmium-mediated oxidative cleavage of the corresponding 2-vinyl derivatives. Reduction of the 2-formyl compounds gave the corresponding 2-hydroxymethyl derivatives, which are key interm
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