Bioorganic and Medicinal Chemistry p. 3068 - 3076 (2017)
Update date:2022-08-02
Topics:
Nencetti, Susanna
La Motta, Concettina
Rossello, Armando
Sartini, Stefania
Nuti, Elisa
Ciccone, Lidia
Orlandini, Elisabetta
Aldose reductase (ALR2), a NADPH-dependent reductase, is the first and rate-limiting enzyme of the polyol pathway of glucose metabolism and is implicated in the pathogenesis of secondary diabetic complications. In the last decades, this enzyme has been ta
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