Tetrahedron Letters p. 5341 - 5344 (1999)
Update date:2022-08-03
Topics:
Iwabuchi, Yoshiharu
Kurihara, Shinwa
Oda, Motoko
Fujii, Ikuo
Esterolytic abzymes were generated via immunization with a haptenic diphosphonate mounted with two distinct traps actuated by the 'bait and switch' and 'transition-state mimic' concepts. One monoclonal antibody, 12F12, was characterized in detail, and showed significant rate enhancement and unique substrate specificity. Experimental data support that the antibody catalyzes the reactions with a concerted catalytic mechanism.
View MoreSpringchem New Material Technology Co.,Limited
website:http://www.spring-chem.com
Contact:86-21-62885108
Address:602B, Building 1, No. 641, Tianshan Road
Chongqing Yawei Fine Chemical Co.,Ltd
Contact:0086-23-62849407
Address:Ziyou village, Nanquan town, Banan district, Chongqing China
Shanghai Harvest Chemical Ind. Co., Ltd.
Contact:021-51385350
Address:ROOM 806-807, AI LI CHEN BUILDING, No.333 JINGXIANG ROAD, PUDONG DISTRICT, 201206, SHANGHAI
Contact:+86 18616952870
Address:Area
Shenzhen JYMed Technology Co.,Ltd.
website:http://www.jymedtech.com
Contact:+86-755-26612112
Address:1#8,9/F, Biomedicine innovation Industrial Park, No.14, Jinhui Road, Pingshan Sistrict, Shenzhen, China
Doi:10.1016/S0040-4039(00)79216-1
(1993)Doi:10.1055/s-2005-921932
(2005)Doi:10.1246/bcsj.52.1478
(1979)Doi:10.1021/acs.orglett.5b03003
(2015)Doi:10.1016/j.tetlet.2009.06.109
(2009)Doi:10.1021/jm00292a049
(1971)
