Synthesis of new (benzimidazolyl)piperazines with affinity for the 5- HT(1A) receptor via Pd(0) amination of bromobenzimidazoles

DOI: 10.1016/S0960-894X(99)00384-4

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2339 - 2342 (1999)

Update date:2022-08-04

Topics:

Authors:

Lopez-Rodriguez, Maria L.

Viso, Alma

Benhamu, Bellinda

Rominguera, J. Luis

Murcia, Marta

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(99)00384-4

The synthesis of a new family of (benzimidazolyl)piperazines has been developed through Pd(0) mediated amination of 4- and 6-bromobenzimidazole derivatives. Preliminary studies showed that some of these compounds are potent 5-HT(1A) receptor ligands.

Full text of DOI:10.1016/S0960-894X(99)00384-4

Products guided by the article

Product name:6-bromo-1-trityl-1H-benzo[d]imidazole

Cas No:247083-09-6

R&D Labs maybe for 247083-09-6

Weifang Yukai Chemical Co.,Ltd.

website:http://www.yukaichem.com/en.html

Contact:+86-536-8865336

Address:binhai economic development zone，262737 shangdong，china
Changsha Yonta Industry Co., Ltd.

Contact:+ 86-731-8535 2228

Address:Rm.1717, North Bldg., No.368, East 2nd Ring Road(2nd Section)
TIANJIN FESTO CHEMICAL CO.,LTD(expird)

Contact:86-22-25814570

Address:No.12th,5th Ave.,TEDA,Tianjin,China
Huaihua Baohua Biotechnology Co.,Ltd

website:http://www.baochengchem.com

Contact:86-519-82698291

Address:HouYang chemical development zone,Jintan,Jiangsu,China (213200)
Shanggao Ruiya Fine Chemicals Co., Ltd

Contact:+86-795-2592103

Address:Xingguang Nanlu,Shanggao County Industry Park

Relevant to this article

Organophosphorus compounds; 142:¹ A simple approach to 1,2,4-selena-and telluradiphospholes from phosphaalkynes and the chalcogen elements and a first study of their reactivity

Doi:10.1055/s-1999-3573
(1999)
Site-specific RNA cleavage using terpyridine · Cu(II)-linked 2'-O- methyloligonucleotides

Doi:10.1080/07328319908044769
(1999)
Discovery of new leads against Mycobacterium tuberculosis using scaffold hopping and shape based similarity

Doi:10.1016/j.bmc.2017.07.034
(2017)
Synthesis of alkyl esters of 4-amino-2-sulfamoylbenzoic acid.

Doi:10.1002/jps.2600520126
(1963)
Syntheses of corticotropin peptides. IX. Synthesis of [1-glycine]-ACTH(1-18)-octadecapeptide amide.

Doi:10.1246/bcsj.43.196
(1970)
trans-3,4-Disubstituted pyrrolidines by 1,3-dipolar cycloaddition: Enantioselective approaches and their limitations

Doi:10.1016/S0957-4166(99)00244-X
(1999)

Article Doi