Cycloaromatization of methyl (E)-4-(methyllithio)-3-(1-pyrrolidinyl)-2-butenoate with α-oxoketene N,S-acetals: Direct synthesis of 3,5-bis(cycloalkylamino)biphenyls

DOI: 10.1055/s-1995-4029

Source and publish data:

Synthesis p. 929 - 930 (1995)

Update date:2022-08-02

Topics:

Authors:

Reddy Reddy

Ila Ila

Junjappa

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Article abstract of DOI:10.1055/s-1995-4029

The vinyl carbanion 2 undergoes cycloaromatization with α-oxoketene N,S-acetals 3 through 1,4-conjugate addition-elimination process to afford 3,5-diaminobiphenyls 4 in good yields.

Full text of DOI:10.1055/s-1995-4029

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